Abstract:
Mobile, affordable and reliable biochemical sensors that can drastically reduce the detection time by enabling multiple biomarker detection from small sample volumes are essential for effective next-generation healthcare. Unfortunately, current biosensing methods require laboratory infrastructure, trained personnel, and complex and costly bioassay protocols. As such, these methods are not suitable for point-of-care and lab-on-a-chip applications. On the other hand, nanophotonic biosensors can detect biomolecules in a label-free and non-destructive manner, leveraging enhanced light-matter interactions at nanoengineered surfaces. In this talk, I will begin by giving an overview on plasmonic biosensors and introduce different optical interrogation schemes, including intensity-based imaging and phase-based interferometric optics. In particular, I will present portable bioanalytical optical platforms for on-site deployment and highlight the results from a clinical study designed to detect Sepsis biomarkers from patient samples. Second, I will demonstrate the use of high-Q dielectric metasurfaces for ultrasensitive biomolecule detection. Here, I will emphasize the importance of hyperspectral imaging optics, which enable spatially-resolved spectral data acquisition. Moreover, I will present a unique multiresonant dielectric metasurface designed for spectrometerless optical characterization of a single-layer graphene over large areas.
Biography:
Dr. Filiz Yesilkoy received her Ph.D. degrees in Electrical Engineering from the University of Maryland, College Park, USA in 2013. She was awarded the Fulbright Foreign Student Scholarship, presented by the US State department to the academically distinguished foreign students. During her graduate studies, Dr. Yesilkoy received the UMD Ann G. Wylie Dissertation Fellowship, the Future Faculty Fellowship, the Distinguished Teaching Assistant Award, and the Graduate Student Service Award for her efforts in supporting female students as president of the Women in ECE association. Dr. Yesilkoy worked as a postdoctoral researcher in Prof. Brugger’s laboratory at the École polytechnique fédérale de Lausanne (EPFL) from 2013 until 2015, during which time she spent one year at the University of Tokyo as a guest researcher in Prof. Kim’s group. Currently, she is a postdoctoral researcher in Prof. Altug’s laboratory at EPFL, working in the field of bio-nano-photonic systems for the development of next-generation optical biosensors. Her research interests include experimental and theoretical aspects of nano-electronic and nano-photonic devices, scalable nanofabrication methods for low-cost and high-throughput manufacturing, visible to mid-IR spectroscopy, and imaging optics for biomedical applications. In 2018, she was elected chair of OSA’s Optical Biosensors Technical Group.
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