Abstract: Fluorescence microscopy has long been a valuable tool for biological and biomedical imaging. Control of optical parameters such as the amplitude, phase, coherence, polarization, and propagation angle of light gives great capabilities to fluorescence imaging techniques, ranging from nanoscale resolution to long-term observation of living cells. In this talk, I present my group’s effort to use tailored light in fluorescence microscopy and show its great potential in imaging based transcriptomics and proteomics. I also present a 4D nucleome project which will shed new light on nuclear dynamics in cell biology.
Biography: Han received his Ph.D. in Physical Chemistry from Seoul National University, South Korea. During his PhD, he worked at Max Planck Institute for Biophysical Chemistry where he contributed to development of STED microscopy. During his postdoc at University of Illinois at Urbana-Champaign, he designed new optical tools for biological applications, such as studying DNA-protein interactions and RNA imaging in live-cells. Since 2016, he has been an assistant professor at CREOL and developing next-generation fluorescence imaging techniques for biomedical applications. He was awarded the NIH MIRA for Early Stage Investigators.
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